Isdale A H
Rheumatology and Rehabilitation Research Unit, University of Leeds, United Kingdom.
Ann Rheum Dis. 1993 Sep;52(9):681-4. doi: 10.1136/ard.52.9.681.
To draw attention to and detail the features of stress fractures of the pubic rami in patients with rheumatoid arthritis (RA).
Twenty two cases were collected prospectively over a four year period from patients undergoing active rheumatological surveillance in Leeds. Both old and new fractures were included. Information was obtained from the patients, clinical notes, and radiological investigations.
All patients were women (mean age 68.1 years) with longstanding (mean disease duration 24.2 years) seropositive RA. Nineteen (86%) were receiving regular prednisolone treatment and all patients had radiological evidence of osteoporosis, with vertebral crush fractures in 10 (63%) of the 16 who had vertebral x ray examination. There was no biochemical evidence of osteomalacia. Nineteen (86%) presented with pain in the low back, groin, or hip and three were asymptomatic. Pain developed gradually in seven with an acute onset in the remainder. Six gave a history of a fall but only seven were x rayed at the onset of symptoms and initial radiographs were negative in five of these. In eighteen the fracture had either minimal or no effect on their mobility. Fractures affected all four pubic rami and in four all four were fractured. All but one patient (who had multiple fractures) made an uneventful recovery over two to four weeks with conservative management.
Stress fractures of the pubic rami in RA appear to be more common than had been recognised. The low grade nature of symptoms, the minimal effect on mobility, and the absence of significant trauma are typical features and suggest that many more stress fractures may go unrecognised.
引起对类风湿关节炎(RA)患者耻骨支应力性骨折特征的关注并详细阐述。
在四年期间前瞻性收集了利兹市接受积极风湿病监测患者中的22例病例。新旧骨折均包括在内。从患者、临床记录和影像学检查中获取信息。
所有患者均为女性(平均年龄68.1岁),患有长期(平均病程24.2年)血清学阳性的RA。19例(86%)接受常规泼尼松龙治疗,所有患者均有骨质疏松的影像学证据,16例接受脊椎X线检查的患者中有10例(63%)有椎体压缩骨折。没有骨软化的生化证据。19例(86%)表现为腰、腹股沟或髋部疼痛,3例无症状。7例疼痛逐渐出现,其余为急性发作。6例有跌倒史,但只有7例在症状发作时进行了X线检查,其中5例初始X线片为阴性。18例患者的骨折对其活动能力影响极小或无影响。骨折累及所有四个耻骨支,4例患者四个耻骨支均骨折。除1例(有多发性骨折)外,所有患者经保守治疗在两至四周内顺利康复。
RA患者耻骨支应力性骨折似乎比以往认识的更为常见。症状程度较轻、对活动能力影响极小以及无明显创伤是典型特征,这表明可能有更多的应力性骨折未被识别。