Massimo C G, Presenti L F, Favi P P, Crisci C, Cruz Guadrón E A
University of Florence, Italy.
Ann Thorac Surg. 1993 Nov;56(5):1110-6. doi: 10.1016/0003-4975(95)90026-8.
From June 1985 to December 1991, 21 patients (12 men and 9 women; mean age, 60 years) underwent total simultaneous aortic replacement that extended from the valve to the bifurcation. The causes of the diseased aorta were: medial degeneration with total aortic dilatation or multiple aneurysms (n = 7) and either acute (n = 4) or chronic (n = 10) dissection. Clinical evaluation and investigation in all patients consisted of computed tomography and magnetic resonance imaging as well as angiography. Only patients with combined thoracic and abdominal emergencies were selected, and these comprised worsening of cardiac conditions resulting from aortic regurgitation, and rapid dilatation of the ascending aorta and arch with impending rupture in conjunction with ischemia of the abdominal viscera, kidney, or either leg. The surgical technique consisted of inducing deep hypothermia by means of femoral vein-femoral artery cardiopulmonary bypass. During the cooling time, the aortic root was replaced under cardioplegia. Once lowering of the body temperature attained electroencephalographic silence, circulation was stopped and the aorta was replaced from the arch to the bifurcation. Circulation and rewarming were resumed only after the operation was completed. In our most recent patient, the operating time was reduced by opening the thoracic and the abdominal incisions during cooling; the cardioplegic solution as not injected but, instead, the myocardium was cooled down along with the whole body. In these patients, the hypothermy at electroencephalographic silence ranged from 14 degrees to 19 degrees C.(ABSTRACT TRUNCATED AT 250 WORDS)
1985年6月至1991年12月,21例患者(12例男性,9例女性;平均年龄60岁)接受了从瓣膜至分叉处的全同期主动脉置换术。病变主动脉的病因包括:中层退变伴主动脉全程扩张或多发动脉瘤(7例),以及急性(4例)或慢性(10例)夹层。所有患者均进行了临床评估及计算机断层扫描、磁共振成像和血管造影检查。仅选择合并胸腹部急症的患者,包括因主动脉反流导致心脏状况恶化,升主动脉和主动脉弓快速扩张并即将破裂,同时伴有腹部脏器、肾脏或下肢缺血。手术技术包括通过股静脉-股动脉体外循环诱导深度低温。在降温期间,在心脏停搏下置换主动脉根部。一旦体温降至脑电图静息状态,停止循环并从主动脉弓至分叉处置换主动脉。仅在手术完成后恢复循环和复温。在我们最近的患者中,通过在降温期间打开胸腹部切口减少了手术时间;未注入心脏停搏液,而是随着全身一起冷却心肌。在这些患者中,脑电图静息状态下的体温范围为14℃至19℃。(摘要截选至250字)