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二尖瓣狭窄的首例成功外科治疗:埃利奥特·卡特勒二尖瓣分离术70周年

The first successful surgical treatment of mitral stenosis: the 70th anniversary of Elliot Cutler's mitral commissurotomy.

作者信息

Cohn L H

机构信息

Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, Massachusetts 02115.

出版信息

Ann Thorac Surg. 1993 Nov;56(5):1187-90. doi: 10.1016/0003-4975(95)90049-7.

Abstract

In 1923 Elliot Carr Cutler, in conjunction with his cardiology colleague, Samuel Levine, performed a closed transventricular mitral commissurotomy with a tenotomy knife on a 12-year-old patient dying of rheumatic mitral stenosis at the Peter Bent Brigham Hospital. This operation was carried out after several years of experimentation regarding resuscitation of the heart, appropriate incisions, and the pathophysiology of mitral stenosis. The interest in mitral stenosis was rampant at the time because of the huge number of patients suffering from this public health problem. The patient survived and went on to die of pneumonia 4 years postoperatively. Subsequent to this, Cutler performed seven more operations using his new cardiovalvulotome, which was to create controlled mitral regurgitation. Unfortunately, this concept did not promote long-term success and a moratorium for these operations was called in 1929. Nevertheless, this pioneering effort in 1923 was the first successful operation to treat valvular heart disease by a surgical technique.

摘要

1923年,埃利奥特·卡尔·卡特勒与其心脏病学同事塞缪尔·莱文在彼得·本特·布里格姆医院,对一名因风湿性二尖瓣狭窄濒临死亡的12岁患者,使用腱刀进行了闭式经心室二尖瓣交界切开术。该手术是在经过数年关于心脏复苏、合适切口以及二尖瓣狭窄病理生理学的实验后开展的。当时,由于大量患者受此公共卫生问题困扰,对二尖瓣狭窄的研究兴趣高涨。该患者存活了下来,但术后4年死于肺炎。此后,卡特勒又使用他新的心脏瓣膜刀进行了七次手术,目的是制造可控的二尖瓣反流。不幸的是,这一理念并未带来长期成功,1929年此类手术被暂停。尽管如此,1923年的这一开拓性努力是首例通过外科技术成功治疗瓣膜性心脏病的手术。

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