西多恩衍生物：合成与抗菌活性。
Sydnone derivatives: synthesis and antimicrobial activity.
作者信息
Pilli H G, Safak C, Abbasoğlu U
机构信息
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
出版信息
Arch Pharm (Weinheim). 1993 Sep;326(9):559-61. doi: 10.1002/ardp.19933260912.
Amongst a number of mesoionic compounds studied so far, sydnones have attained importance due not only to their structural features and chemical properties, but also to their biological properties. Sydnone derivatives have been extensively studied for their biological activities, the antimicrobial activity of substituted aryl sydnones has been reported. Aryl sydnones are less toxic and more active than alkyl sydnones. Also chalcone analogues are known to have antimicrobial activity.
在迄今为止研究的众多介离子化合物中，斯德酮不仅因其结构特征和化学性质，还因其生物学性质而变得重要。斯德酮衍生物因其生物活性已被广泛研究，已报道了取代芳基斯德酮的抗菌活性。芳基斯德酮比烷基斯德酮毒性更小且活性更高。此外，已知查尔酮类似物具有抗菌活性。
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