补骨脂素加长波紫外线疗法的眼部并发症。

Ocular complications of PUVA therapy.

作者信息

See J A, Weller P

机构信息

Skin and Cancer Foundation, Sydney, NSW.

出版信息

Australas J Dermatol. 1993;34(1):1-4. doi: 10.1111/j.1440-0960.1993.tb00834.x.

DOI:10.1111/j.1440-0960.1993.tb00834.x

PMID:8240180

Abstract

PUVA, the combination of psoralen and long wave ultraviolet radiation is widely used in the management of psoriasis, vitiligo and several other dermatological disorders. The potential for long term treatment to cause ocular damage remains to be determined and despite the large numbers of patients who have received PUVA treatment, development of cataract is exceedingly rare. This paper discusses cataract formation, reviews the literature concerning the ocular complications of PUVA therapy and proposes guidelines for ocular protection during photochemotherapy.

摘要

补骨脂素与长波紫外线辐射联合应用的光化学疗法（PUVA）广泛用于银屑病、白癜风及其他几种皮肤病的治疗。长期治疗导致眼部损伤的可能性尚待确定，尽管有大量患者接受过PUVA治疗，但白内障的发生极为罕见。本文讨论了白内障的形成，回顾了有关PUVA治疗眼部并发症的文献，并提出了光化学疗法期间眼部保护的指导原则。