Department of Ophthalmology, The University of Iowa, Iowa City, IA, USA.
Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Am J Clin Dermatol. 2022 Jan;23(1):51-60. doi: 10.1007/s40257-021-00648-x. Epub 2021 Nov 3.
Psoriasis is a chronic immune-mediated inflammatory skin condition that commonly presents with red, thickened, and scaling plaques. Given the prominent cutaneous manifestations of psoriasis, more subtle ophthalmic findings of the disease may initially go undetected, with the potential for significant ocular morbidity. Associated ocular disease can involve nearly any structure of the eye, with the eyelids most commonly being affected, resulting in relatively common signs and symptoms of ocular surface discomfort. The presence of intraocular inflammation (i.e., uveitis) or retinal involvement carry a heightened risk of vision loss, and are often more difficult to diagnose outside of the ophthalmology clinic. Early detection and treatment of ocular disease can limit morbidity and are critical to the management of these patients, which requires coordination of care between dermatologists and ophthalmologists. The objective of this article was to review the most common ocular conditions that affect psoriatic patients, when to consider referral to an ophthalmologist, and to summarize the adverse ocular effects of current psoriasis treatments.
银屑病是一种慢性免疫介导的炎症性皮肤疾病，通常表现为红色、增厚和鳞屑斑块。鉴于银屑病的明显皮肤表现，疾病的更微妙的眼部表现最初可能未被发现，具有显著的眼部发病率的潜在风险。相关的眼部疾病几乎可以涉及眼睛的任何结构，最常见的是眼睑受累，导致相对常见的眼表面不适的迹象和症状。眼内炎症（即葡萄膜炎）或视网膜受累会增加视力丧失的风险，并且通常在眼科诊所之外更难诊断。眼部疾病的早期发现和治疗可以降低发病率，对于这些患者的治疗至关重要，这需要皮肤科医生和眼科医生之间的护理协调。本文的目的是回顾影响银屑病患者的最常见的眼部疾病，何时考虑转介给眼科医生，并总结当前银屑病治疗的眼部不良反应。
