闭塞性细支气管炎伴机化性肺炎与原发性混合性冷球蛋白血症相关。

Bronchiolitis obliterans organizing pneumonia associated with essential mixed cryoglobulinemia.

作者信息

Zackrison L H, Katz P

机构信息

Division of Rheumatology, Immunology, Georgetown University Medical Center, Washington, DC 20007.

出版信息

Arthritis Rheum. 1993 Nov;36(11):1627-30. doi: 10.1002/art.1780361119.

DOI:10.1002/art.1780361119

PMID:8240440

Abstract

Bronchiolitis obliterans organizing pneumonia (BOOP) is an uncommon and underrecognized pathologic finding observed in a variety of syndromes including connective tissue diseases. Although lung involvement in essential mixed cryoglobulinemia (EMC) has been reported, there are no previous reports of BOOP in EMC. We report herein a case of longstanding EMC associated with interstitial and cavitary lung disease histologically consistent with BOOP. A theory of a possible etiologic basis for the development of BOOP in patients with connective tissue diseases is discussed.

摘要

闭塞性细支气管炎伴机化性肺炎（BOOP）是一种在包括结缔组织病在内的多种综合征中观察到的罕见且未被充分认识的病理表现。尽管已有报道称原发性混合性冷球蛋白血症（EMC）可累及肺部，但此前尚无EMC合并BOOP的报道。我们在此报告一例长期EMC合并组织学表现符合BOOP的间质性和空洞性肺疾病。本文还讨论了结缔组织病患者发生BOOP可能的病因学基础理论。