Gaffan D, Harrison S
Department of Experimental Psychology, Oxford University, UK.
Behav Brain Res. 1993 Sep 30;56(2):119-25. doi: 10.1016/0166-4328(93)90029-p.
Cynomolgus monkeys (Macaca fascicularis) learned a series of visuospatial configural discriminations in which particular discriminative stimulus objects were rewarded only in particular spatial locations. For example, object X was rewarded if it was on the left but not if it was on the right. After ablation of part of the dorsal prestriate cortex they were impaired in learning discriminations of this kind. The same animals were not impaired in learning visual object discriminations in which spatial position was irrelevant, nor in learning spatial discriminations in which object identity was irrelevant. The results were compared with previously reported results from fornix transection in the same tasks; the deficit following dorsal prestriate ablation in visuospatial configural discrimination learning was similar in severity to that which followed fornix transection. The results show that the dorsal prestriate area has a more general role in visuospatial processing than was known hitherto, and they suggest that it interacts with the hippocampal formation and fornix in visuospatial memory tasks.
食蟹猴（猕猴）学会了一系列视觉空间构型辨别任务，其中特定的辨别性刺激物体只有在特定的空间位置才会得到奖励。例如，物体X如果在左边则会得到奖励，而在右边则不会。在切除部分背侧纹前皮质后，它们在学习此类辨别任务时受到了损害。同样的动物在学习与空间位置无关的视觉物体辨别任务时，以及在学习与物体身份无关的空间辨别任务时，并未受到损害。将这些结果与之前报道的在相同任务中进行穹窿横切后的结果进行了比较；背侧纹前皮质切除后在视觉空间构型辨别学习中的缺陷，其严重程度与穹窿横切后的相似。结果表明，背侧纹前皮质在视觉空间处理中所起的作用比迄今所知的更为普遍，并且表明它在视觉空间记忆任务中与海马结构和穹窿相互作用。
