Sastry S K, Horwitz A F
Department of Biochemistry, University of Illinois, Urbana 61801.
Curr Opin Cell Biol. 1993 Oct;5(5):819-31. doi: 10.1016/0955-0674(93)90031-k.
The integrin cytoplasmic domains are generally short amino acid sequences that are highly divergent among alpha-subunits and partially conserved among beta-subunits. Interest in them has increased over the past few years as they have been shown to mediate several kinds of transmembrane signaling events as well as structural connections between the extracellular matrix and the cytoskeleton.
整合素细胞质结构域通常是短氨基酸序列，在α亚基之间高度不同，在β亚基之间部分保守。在过去几年中，人们对它们的兴趣有所增加，因为它们已被证明可介导多种跨膜信号传导事件以及细胞外基质与细胞骨架之间的结构连接。
