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Cloning and sequence of a chicken alpha-N-acetylgalactosaminidase gene.

作者信息

Davis M O, Hata D J, Smith D, Walker J C

机构信息

Division of Biological Sciences, University of Missouri-Columbia 65211.

出版信息

Biochim Biophys Acta. 1993 Nov 16;1216(2):296-8. doi: 10.1016/0167-4781(93)90158-a.

DOI:10.1016/0167-4781(93)90158-a
PMID:8241271
Abstract

A cDNA clone encoding the mature polypeptide for the chicken liver alpha-N-acetylgalactosaminidase enzyme was isolated by screening a cDNA library with a synthetic sequence derived from the human alpha-N-acetylgalactosaminidase gene. The deduced amino acid sequence of the chicken liver clone was identical to the amino-terminal and cyanogen bromide derived peptide sequences obtained from the purified enzyme. The chicken enzyme has 75% identity with the human alpha-N-acetylgalactosaminidase and 56-33% identity with alpha-galactosidases from several sources.

摘要

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