Binding of (T,G)-A--L by normal sera.

The synthetic polypeptide poly-L-(Tyr, Glu)-poly-DL-Ala--poly-L-Lys [(T,G)-A--L] was found to be bound not only by mouse immune serum, but also by nonimmune sera from several species. A combination of immunoelectrophoresis and autoradiography showed that albumin, beta-globulins and immunoglobulins in these sera may bind the antigen. This binding pattern is different, however, for the various species investigated.