Goodman D, Irvin T T
Department of Surgery, Royal Devon and Exeter Hospital, UK.
Br J Surg. 1993 Oct;80(10):1327-9. doi: 10.1002/bjs.1800801037.
Of 152 consecutive patients with carcinoma of the right colon, 61 (40 per cent) suffered delays in treatment of more than 12 weeks from the onset of symptoms, with a mean delay of 48 weeks. The most common error was failure to initiate or complete the investigation of iron-deficiency anaemia (33 patients). False-negative barium enema investigations occurred in 16 cases. Patients with delays in diagnosis had survival rates not significantly different from those who presented early. Thirty-one patients with anaemia and no abdominal symptoms had a significantly higher survival rate than 30 presenting with abdominal symptoms, despite delays in treatment (P < 0.02). Greater vigilance is required in the investigation of patients presenting with iron-deficiency anaemia.
在152例连续性右半结肠癌患者中,61例(40%)从症状出现到开始治疗延误超过12周,平均延误48周。最常见的失误是未启动或完成缺铁性贫血的检查(33例患者)。16例钡剂灌肠检查结果为假阴性。诊断延误的患者生存率与早期就诊患者的生存率无显著差异。31例有贫血但无腹部症状的患者,尽管治疗有延误,但其生存率显著高于30例有腹部症状的患者(P<0.02)。对缺铁性贫血患者进行检查时需要提高警惕。