Holliday H W, Hardcastle J D
Lancet. 1979 Feb 10;1(8111):309-11. doi: 10.1016/s0140-6736(79)90718-9.
Mean delay between the onset of symptoms and treatment was 30.5 weeks in a hundred patients with colonic carcinoma and 38 weeks in a hundred patients with rectal carcinoma. Most of this delay occurred outside hospital and delays attributable to the patient and family doctor were almost equal in duration. Patient delay is largely the result of not knowing the importance of bowel symptoms, while delay with the family doctor was the result of not examining patients with possible rectal carcinomas and not recognising symptoms suggestive of colonic carcinoma. 42% of patients with colonic carcinoma were admitted for emergency treatment, 76% having already consulted their doctor about symptoms on one or more occasions. Hospital delay consisted mainly in waiting for investigations, poor quality barium enemas, and inadequate sigmoidoscopy. There was no relation between the duration of symptoms and the Dukes stage of the tumour.
100例结肠癌患者症状出现至治疗的平均延迟时间为30.5周，100例直肠癌患者为38周。这种延迟大多发生在院外，患者及家庭医生造成的延迟时间几乎相等。患者延迟主要是因为不了解肠道症状的重要性，而家庭医生造成的延迟是由于未对可能患有直肠癌的患者进行检查，以及未识别出提示结肠癌的症状。42%的结肠癌患者因急诊入院，其中76%已就症状咨询过医生一次或多次。医院延迟主要包括等待检查、钡灌肠质量差和乙状结肠镜检查不充分。症状持续时间与肿瘤的Dukes分期之间没有关系。
