Shimizu N, Ohnishi S, Satoh K, Tohyama M
Arch Histol Jpn. 1978 Apr;41(2):103-12. doi: 10.1679/aohc1950.41.103.
The locus coeruleus (LC) of rats at different ages was studied in sections stained by the Golgi-rapid method. The LC is composed of two types of neurons, medium-sized (20mu x 35mu) and small cells (10mu x 15mu). The medium-sized cells are mainly fusiform in shape and occupy the dorso-caudal part of the nucleus, while pyramidal or multipolar cells frequently occur in the ventral part. Both types of cells bear a moderate to large number of spines on the surface of their soma, which form the main criterion for identifying the LC neurons. Though they radiate several relatively short dendrites in different directions, which bifurcate once or twice, the medio-ventral ramification is prevailing, extending beyond the limit of cells to the pontine central gray adjacent to the LC. The latter region might constitute the principal receptive sites of LC for inputs from various origins. Axons of LC neurons take their initial course either latero-rostral- or latero-caudalwards, while some axons divide dichotomously rostral- and caudalwards. Fine axon collaterals are frequently demonstrated within the LC and sometimes seem to contact with dentrites of LC neurons. Besides this, two kinds of afferents of unknown origins are observed between LC neurons. At least three kinds of small oval neurons are occasionally impregnated, though their axonal distributions cannot be demonstrated.
采用高尔基快速染色法对不同年龄大鼠的蓝斑进行了研究。蓝斑由两种神经元组成，即中型（20微米×35微米）和小型细胞（10微米×15微米）。中型细胞主要呈梭形，占据核的背尾部分，而锥体或多极细胞则常见于腹侧部分。两种类型的细胞在其胞体表面都有中等数量到大量的棘突，这是识别蓝斑神经元的主要标准。尽管它们向不同方向发出几条相对较短的树突，这些树突会分支一到两次，但中腹侧分支占主导，延伸到细胞界限之外，到达与蓝斑相邻的脑桥中央灰质。后一区域可能构成蓝斑接收来自各种来源输入的主要部位。蓝斑神经元的轴突最初要么向外侧-头侧或外侧-尾侧走行，而一些轴突在头侧和尾侧二分。在蓝斑内经常可见细的轴突侧支，有时似乎与蓝斑神经元的树突接触。除此之外，在蓝斑神经元之间观察到两种来源不明的传入纤维。偶尔会染出至少三种小的椭圆形神经元，尽管它们的轴突分布无法显示。
