Evans D E, Alter W A, Shatsky S A, Gunby E N
J Neurosurg. 1976 Dec;45(6):609-16. doi: 10.3171/jns.1976.45.6.0609.
The cardiovascular events resulting from experimental head injury were studied to determine the incidence of cardiac arrhythmias and to define the autonomic mechanisms responsible for these changes. Electrocardiograms and arterial blood pressure were recorded in anesthetized monkeys before and after the animals were subjected to temporoparietal head impact. Cardiac arrhythmias and hypotension occurred immediately following impact in every animal studied. Various atrioventricular nodal and ventricular arrhythmias were seen. Cholinergic blockage was found to prevent arrhythmias induced by head injury whereas adrenergic blockage was found to be ineffective.
研究了实验性头部损伤导致的心血管事件，以确定心律失常的发生率，并明确导致这些变化的自主神经机制。在麻醉的猴子遭受颞顶头部撞击之前和之后，记录其心电图和动脉血压。在每只被研究的动物中，撞击后立即出现心律失常和低血压。观察到各种房室结和室性心律失常。发现胆碱能阻滞可预防头部损伤诱发的心律失常，而肾上腺素能阻滞则无效。
