儿童神经纤维瘤病：25例病例回顾

Neurofibromatosis in childhood: a review of 25 cases.

作者信息

Pollnitz R

出版信息

Med J Aust. 1976 Jul 10;2(2):49-52. doi: 10.5694/j.1326-5377.1976.tb117619.x.

DOI:10.5694/j.1326-5377.1976.tb117619.x

Abstract

The initial symptoms and signs of neurofibromatosis in 25 children are reported, and the literature is briefly reviewed. Two little known associations of neurofibromatosis are revealed. Four children showed hydrocephalus related to stricture of the aqueduct of Sylvius. Four other children presented with failure to thrive in infancy which was regarded in retrospect as a non-specific association of neurofibromatosis. It is emphasized that such manifestations may be the presenting features of neurofibromatosis in children.

摘要

报告了25例儿童神经纤维瘤病的初始症状和体征，并对相关文献进行了简要回顾。揭示了神经纤维瘤病两个鲜为人知的关联。4名儿童出现与中脑导水管狭窄相关的脑积水。另外4名儿童在婴儿期出现生长发育迟缓，回顾起来这被视为神经纤维瘤病的一种非特异性关联。强调这些表现可能是儿童神经纤维瘤病的首发特征。