Crawford M J, Buckler J M
Dev Med Child Neurol. 1983 Jun;25(3):370-3. doi: 10.1111/j.1469-8749.1983.tb13774.x.
Monozygotic twins with neurofibromatosis both showed accelerated growth in association with optic glioma. Endocrine abnormalities were similar, but only one of the two had precocious puberty. This identical presentation in twins supports the view that the site of tumour formation is determined during intra-uterine development.
患有神经纤维瘤病的同卵双胞胎均表现出与视神经胶质瘤相关的生长加速。内分泌异常情况相似,但两人中只有一人出现性早熟。双胞胎的这种相同表现支持了肿瘤形成部位在子宫内发育期间就已确定的观点。