Cooper E H, Bunning R, Illingworth S, Späti B, Child J A
Biomedicine. 1978 Jul;29(5):154-8.
Long-term observation of non-Hodgkin's lymphomas indicates they can be sub-divided into two groups with respect to changes in the plasma proteins. The first group has acute phase reactant proteins raised during active disease and sometimes a raised B2m, whilst in remission the protein profile is normal. The second group is typified by a chronic elevation of B2m and ESR but has normal C-RP levels. Chronic lymphocytic leukaemia usually has a raised B2 m level and normal acute phase proteins, a subset with low B2 m is described.
对非霍奇金淋巴瘤的长期观察表明,就血浆蛋白变化而言,它们可分为两组。第一组在疾病活动期急性期反应蛋白升高,有时B2m也升高,而在缓解期蛋白谱正常。第二组的典型特征是B2m和红细胞沉降率(ESR)持续升高,但C反应蛋白(C-RP)水平正常。慢性淋巴细胞白血病通常B2m水平升高,急性期蛋白正常,也描述了一个B2m水平低的亚组。