Ciatto S, Bonardi R, Rosselli del Turco M
Centro per lo Studio e la Prevenzione Oncologica, Firenze.
Radiol Med. 1993 Oct;86(4):467-71.
The authors report the results of the Florence District program for the year 1992. 11,033 subjects were examined. Attendance rate (64.4%) was significantly related to age (42-49 = 71.0%; 50-59 = 66.7%; 60-70 = 58.5%). Recall rate to diagnostic assessment was 2.09% (mammographic abnormalities = 199, subjective symptoms other than pain = 32) and was related to age (42-49 = 3.12%; 50-59 = 1.65%; 60-70 = 1.77%). According to the results of diagnostic assessment 53 surgical biopsies (0.48%) were recommended and performed. The biopsy rate was also related to age (42-49 = 0.2%; 50-59 = 0.4%; 60-70 = 0.7%). Forty-seven carcinomas were detected in 46 subjects (benign/malignant biopsy ratio = 0.13). Cancer detection rate was 0.42% and changed significantly with age (42-49 = 0.13; 50-59 = 0.36; 60-70 = 0.68%), as well as the observed/expected cancer ratio (42-49 = 0.89; 50-59 = 2.03; 60-70 = 2.98). Detected cancers were nonpalpable in 57% of cases. Pathologic staging was pTIS in 2 cases, pT1a in 5, pT1b in 17, pT1c in 17, pT2 in 5, and pT4b in one case. Six of 47 (12.8%) cancers involved axillary nodes. A preliminary estimate of screening cost yielded a total cost of Lit. 397,671,000 for the year 1992--i.e., Lit. 36,000 per examined subject and Lit. 8,461,000 per detected cancer. The results are compared with reference standards for the evaluation of screening performance provided by the national breast screening program in the United Kingdom.
作者报告了1992年佛罗伦萨地区项目的结果。共检查了11,033名受试者。出勤率（64.4%）与年龄显著相关（42 - 49岁 = 71.0%；50 - 59岁 = 66.7%；60 - 70岁 = 58.5%）。诊断评估的召回率为2.09%（乳腺X线摄影异常 = 199例，疼痛以外的主观症状 = 32例），且与年龄相关（42 - 49岁 = 3.12%；50 - 59岁 = 1.65%；60 - 70岁 = 1.77%）。根据诊断评估结果，建议并进行了53例手术活检（0.48%）。活检率也与年龄相关（42 - 49岁 = 0.2%；50 - 59岁 = 0.4%；60 - 70岁 = 0.7%）。在46名受试者中检测到47例癌症（良性/恶性活检比例 = 0.13）。癌症检测率为0.42%，并随年龄显著变化（42 - 49岁 = 0.13；50 - 59岁 = 0.36；60 - 70岁 = 0.68%），以及观察到的/预期的癌症比例（42 - 49岁 = 0.89；50 - 59岁 = 2.03；60 - 70岁 = 2.98）。检测到的癌症中有57%触诊不到。病理分期为pTIS的有2例，pT1a的有5例，pT1b的有17例，pT1c的有17例，pT2的有5例，pT4b的有1例。47例癌症中有6例（12.8%）累及腋窝淋巴结。对筛查成本的初步估计得出1992年的总成本为397,671,000里拉——即每位受检者36,000里拉，每例检测到的癌症8,461,000里拉。将结果与英国国家乳腺筛查项目提供的筛查性能评估参考标准进行了比较。
