Puumala virus infection without signs of renal involvement.

Five cases of Puumala virus infection without renal involvement are described. The main signs were fever, headache, chills and thirst. Pulmonary involvement was also common. Neither increased levels of serum creatinine nor abnormal urinalyses were detected. We suggest that Hantavirus infection is included in the differential diagnosis of any febrile condition when exposure to aerosols from infectious secretions or secretions from rodents is suspected.