Ereniev S I, Semchenko V V, Genne R I, Makovetskiĭ K K
Zh Vyssh Nerv Deiat Im I P Pavlova. 1993 Sep-Oct;43(5):987-93.
Fragments of the embryonic hippocampus, septum, cerebellum and substantia nigra were grafted into the lesioned brain areas of 151 animals with phenotypical (bilateral destruction of the CA1 and CA4 hippocampal areas or the basolateral amygdalar regions in Wistar rats) and genotypic (in Krushinskiĭ-Molodkina strain) high seizure readiness. The parameters of long-term memory were improved after embryonic septal and cerebellar graftings, normalized after embryonic hippocampal graftings and were not improved after embryonic nigral graftings in both strains. Learning ability of the animals of both the strains with ceased audiogenic seizures was kept at the control level after the transplantation of embryonic tissue from the different brain areas. In animals with continued seizures the learning ability normalized after the septal graftings.
将胚胎海马体、隔区、小脑和黑质的片段移植到151只具有表型（Wistar大鼠双侧海马CA1和CA4区或基底外侧杏仁核区域破坏）和基因型（在Krushinskiĭ-Molodkina品系）高癫痫易感性的动物的受损脑区。在两个品系中，胚胎隔区和小脑移植后长期记忆参数得到改善，胚胎海马移植后参数恢复正常，而胚胎黑质移植后则未改善。在移植来自不同脑区的胚胎组织后，两个品系中停止听源性癫痫发作的动物的学习能力保持在对照水平。在仍有癫痫发作的动物中，隔区移植后学习能力恢复正常。
