Evaluation of a glucose oxidase procedure.

A commerical adaptation of Trinder's glucose oxidase procedure for glucose determination was evaluated by regression analysis. Excellent correlation was found between the glucose oxidase procedure and a hexokinase procedure. Good correlation was observed between an AutoAnalyzer I, the SMA 12/60, and a Beckman Glucose Analyzer, all utilizing variations of the glucose oxidase procedure. This combination provides a system that can handle screening, routine, and emergency requests in essentially the same manner and with comparable true glucose results. No interference was found with common anticoagulants and preservatives. Boehringer Mannheim Corporation's kit for glucose determinations appears to be of equivalent quality to the original method as outlined by Trinder and evaluated by others.