Hansen B J, Rosenberg J
Department of Surgical Gastroenterology, Hvidovre University Hospital, Denmark.
Acta Anaesthesiol Scand. 1993 Oct;37(7):643-6. doi: 10.1111/j.1399-6576.1993.tb03781.x.
The pathogenesis of persistent postoperative hiccups is not known. Hiccups can present as a symptom of a subphrenic abscess of gastric distention, and metabolic alterations may also cause hiccups. The hiccups may develop because of increased activity in neural reflex pathways not yet fully defined. Numerous treatment modalities have been tried but with questionable success. Valproate has proven effective in two trials investigating persistent non-surgical hiccups. The simple application of a nasogastric tube may successfully treat the hiccups, possibly because of an alteration of the activity in the reflex neural pathways involved. The available literature on the treatment of persistent hiccups is reviewed, and a treatment protocol for persistent postoperative hiccups is provided.
术后持续性呃逆的发病机制尚不清楚。呃逆可能是膈下脓肿或胃扩张的症状，代谢改变也可能导致呃逆。呃逆可能是由于尚未完全明确的神经反射通路活动增加所致。已经尝试了多种治疗方法，但效果存疑。在两项针对持续性非手术性呃逆的试验中，丙戊酸盐已被证明有效。单纯插入鼻胃管可能成功治疗呃逆，这可能是因为相关反射神经通路的活动发生了改变。本文综述了关于持续性呃逆治疗的现有文献，并提供了术后持续性呃逆的治疗方案。
