Gottfreothsdóttir M S, Gíslason I, Stefánsson E, Sigurjónsdóttir S, Nielsen N C
Department of Ophthalmology, University of Iceland, Landakotsspítalis, Reykjavík.
Acta Ophthalmol (Copenh). 1993 Aug;71(4):544-7. doi: 10.1111/j.1755-3768.1993.tb04633.x.
A prospective double-masked clinical trial was conducted to determine whether retrobulbar bupivacaine block had an effect on post-operative pain, nausea and intra- and post-operative use of analgesics in retinal detachment surgery performed under general anaesthesia. Thirty-two patients were randomized to have general anaesthesia with or without retrobulbar bupivacaine. Pain score was documented as 0-10 (0 = no pain. 10 = worst pain ever felt). Post-operative pain score was significantly lower in the retrobulbar block group during the first post-operative hours than in the control group. Men complained more about post-operative pain than did women. The patients in the retrobulbar group complained less about nausea. Significantly fewer patients in the retrobulbar group required parenteral pain relief during operation and the first 48 h after.
进行了一项前瞻性双盲临床试验,以确定球后布比卡因阻滞对全身麻醉下视网膜脱离手术的术后疼痛、恶心以及术中和术后镇痛药使用情况是否有影响。32例患者被随机分为接受或不接受球后布比卡因全身麻醉两组。疼痛评分记录为0至10分(0 = 无疼痛,10 = 有史以来最严重的疼痛)。球后阻滞组术后最初几个小时的术后疼痛评分显著低于对照组。男性比女性更抱怨术后疼痛。球后阻滞组的患者较少抱怨恶心。球后阻滞组在手术期间及术后48小时内需要非肠道镇痛的患者明显较少。