• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

采用新技术治疗克罗恩病经括约肌型肛瘘

Healing of transsphincteric perianal fistulas in Crohn's disease using a new technique.

作者信息

Winter A M, Banks P A, Petros J G

机构信息

Department of Medicine, St. Elizabeth's Hospital, Boston, Massachusetts.

出版信息

Am J Gastroenterol. 1993 Dec;88(12):2022-5.

PMID:8249967
Abstract

OBJECTIVES

Transsphincteric perianal fistulas in Crohn's disease are often refractory to medical therapy and difficult to treat surgically. Our objective was to determine whether a new method of anal fistulotomy was effective in healing these fistulas.

METHODS

In this new method, the internal opening of the fistula tract was displaced distally to the region of the anal mucosa in 26 patients with Crohn's disease.

RESULTS

Healing was achieved within 5 weeks of surgery in 45/49 (92%) of the fistulas and was not influenced by perioperative medication, site of preexisting Crohn's disease, or condition of the rectum. There has been no alteration of preoperative continence.

CONCLUSIONS

We conclude that this method is highly effective in treating transsphincteric perianal fistulas in Crohn's disease.

摘要

目的

克罗恩病中的经括约肌肛周瘘通常对药物治疗无效且手术治疗困难。我们的目的是确定一种新的肛瘘切开术方法治疗这些瘘管是否有效。

方法

在这种新方法中,对26例克罗恩病患者,将瘘管的内口向远侧移位至肛门黏膜区域。

结果

49个瘘管中有45个(92%)在术后5周内愈合,且不受围手术期用药、原有克罗恩病的部位或直肠状况的影响。术前的控便能力未发生改变。

结论

我们得出结论,该方法治疗克罗恩病中的经括约肌肛周瘘非常有效。

相似文献

1
Healing of transsphincteric perianal fistulas in Crohn's disease using a new technique.采用新技术治疗克罗恩病经括约肌型肛瘘
Am J Gastroenterol. 1993 Dec;88(12):2022-5.
2
Does infliximab infusion impact results of operative treatment for Crohn's perianal fistulas?英夫利昔单抗输注会影响克罗恩病肛周瘘管的手术治疗结果吗?
Dis Colon Rectum. 2007 Nov;50(11):1754-60. doi: 10.1007/s10350-007-9077-3. Epub 2007 Sep 27.
3
Do anal fistulas in Crohn's disease behave differently and defy Goodsall's rule more frequently than fistulas that are cryptoglandular in origin?克罗恩病中的肛瘘与源于隐窝腺性的肛瘘相比,其表现是否不同且更常违背古德索尔法则?
Am J Gastroenterol. 2003 Dec;98(12):2732-5. doi: 10.1111/j.1572-0241.2003.08716.x.
4
Preliminary results on efficacy in closure of transsphincteric and rectovaginal fistulas associated with Crohn's disease using new biomaterials.使用新型生物材料闭合克罗恩病相关经括约肌瘘管和直肠阴道瘘管的疗效初步结果。
Surg Innov. 2009 Jun;16(2):162-8. doi: 10.1177/1553350609338041. Epub 2009 Jun 5.
5
Surgery for Crohn's anal fistulas.克罗恩病肛瘘的手术治疗
J Gastroenterol. 1995 Nov;30 Suppl 8:143-6.
6
Endorectal advancement flap: are there predictors of failure?直肠内推进皮瓣术:是否存在失败的预测因素?
Dis Colon Rectum. 2002 Dec;45(12):1616-21. doi: 10.1097/01.DCR.0000037654.01119.CD.
7
Anti-TNF-alpha (infliximab) used as induction treatment in case of active proctitis in a multistep strategy followed by definitive surgery of complex anal fistulas in Crohn's disease: a preliminary report.抗肿瘤坏死因子-α(英夫利昔单抗)在克罗恩病中用于活动性直肠炎的多步骤诱导治疗,随后对复杂性肛瘘进行确定性手术:一份初步报告。
Dis Colon Rectum. 2005 Apr;48(4):758-67. doi: 10.1007/s10350-004-0828-0.
8
Treatment of perianal fistulas in Crohn's disease by local injection of antibody to TNF-alpha accounts for a favourable clinical response in selected cases: a pilot study.通过局部注射抗TNF-α抗体治疗克罗恩病肛周瘘管在部分病例中取得了良好的临床疗效:一项初步研究。
Scand J Gastroenterol. 2006 Sep;41(9):1064-72. doi: 10.1080/00365520600609941.
9
Adenocarcinoma arising from chronic perianal Crohn's disease: case report and review of the literature.慢性肛周克罗恩病引发的腺癌:病例报告及文献综述
Am Surg. 2008 Jan;74(1):59-61.
10
Biological immunomodulators improve the healing rate in surgically treated perianal Crohn's fistulas.生物免疫调节剂可提高手术治疗的肛周克罗恩病瘘管的愈合率。
Colorectal Dis. 2012 Oct;14(10):1217-23. doi: 10.1111/j.1463-1318.2012.02944.x.

引用本文的文献

1
Imaging techniques and combined medical and surgical treatment of perianal Crohn's disease.肛周克罗恩病的影像学技术及内外科联合治疗
J Ultrasound. 2013 Oct 24;18(1):19-35. doi: 10.1007/s40477-013-0042-9. eCollection 2015 Mar.