Irrmann C, Le Borgne S, Dahlet C, Waller C, Dupeyron J P
Département d'Anesthésiologie, CHU, Strasbourg.
Ann Fr Anesth Reanim. 1993;12(3):247-50. doi: 10.1016/s0750-7658(05)80649-5.
Normovolaemic haemodilution was carried out by erythropheresis by the Blood Bank, 24 to 72 yours before surgery, using a plasmapheresis device. A special disposable haemodilution kit was used, with one plasma and three red cell collection bags and CPD as anticoagulant. Plasma was replaced by 4% albumin. One to 4 red cell packs with 75% haematocrit was obtained and stored for 10 days. This technique is indicated for surgery with an expected blood loss between 1,000 and 1,500 ml, or when the patient cannot be included in a preoperative blood donation programme. The contra-indications are the same as those of intentional normovolaemic haemodilution. This technique has been used in 101 patients due to undergo orthopaedic surgery. Compared with standard haemodilution bags, the advantages of this technique are the excellent asepsis of this product, its 10 days storage and high haematocrit, and the absence of anaesthetic drugs within the bags as well. This technique does not interfere with haemodynamic conditions during anaesthesia; it saves time for both anaesthetists and surgeons. In the authors' experience, this technique has in part replaced the more usual technique.
正常血容量性血液稀释由血库在手术前24至72小时通过血细胞单采术进行，使用血浆置换装置。使用了一种特殊的一次性血液稀释套件，带有一个血浆和三个红细胞采集袋，并使用枸橼酸磷酸盐葡萄糖（CPD）作为抗凝剂。用4%白蛋白替代血浆。获得了1至4个血细胞比容为75%的红细胞包，并储存10天。该技术适用于预期失血量在1000至1500毫升之间的手术，或患者不能纳入术前献血计划的情况。其禁忌症与故意正常血容量性血液稀释相同。该技术已用于101例即将接受骨科手术的患者。与标准血液稀释袋相比，该技术的优点是该产品无菌性极佳、可储存10天且血细胞比容高，并且袋内也没有麻醉药物。该技术在麻醉期间不干扰血流动力学状况；它为麻醉师和外科医生都节省了时间。根据作者的经验，该技术已部分取代了更常用的技术。
