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与无症状骨髓增殖性疾病相关的危及生命的血栓形成和出血问题。

Life-threatening thrombotic and haemorrhagic problems associated with silent myeloproliferative disorders.

作者信息

Vadher B D, Machin S J, Patterson K G, Sukhu C, Walker H

机构信息

Department of Haematology, University College Hospital, London.

出版信息

Br J Haematol. 1993 Sep;85(1):213-6. doi: 10.1111/j.1365-2141.1993.tb08676.x.

Abstract

Myeloproliferative disorders are well recognized as being associated with haemorrhage and thrombosis. We describe two cases, one of life-threatening haemorrhage and the other of thrombosis, in patients with normal peripheral blood counts and films, both of whom went on to develop overt manifestations of myeloproliferative disorders (CGL and essential thrombocythaemia) more than a year after their first presentation.

摘要

骨髓增殖性疾病被公认为与出血和血栓形成有关。我们描述了两例患者,一例出现危及生命的出血,另一例出现血栓形成,这两名患者外周血细胞计数和血涂片均正常,两人在首次就诊一年多后均发展为骨髓增殖性疾病(慢性粒细胞白血病和原发性血小板增多症)的明显表现。

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