Arregui M A, Ratón J A, Landa N, Izu R, Eizaquirre X, Díaz-Pérez J L
Department of Dermatology, Cruces Hospital, Bilbao, Spain.
Clin Exp Dermatol. 1993 Sep;18(5):445-8. doi: 10.1111/j.1365-2230.1993.tb02247.x.
Bazex's acrokeratosis paraneoplastica is a clinically well-defined entity consisting of a distal erythemato-squamous eruption and nail dystrophy. It is always associated with neoplasia, mainly squamous carcinomas of the upper digestive and respiratory tracts; therefore, Bazek's acrokeratosis is considered to be a specific marker of internal malignancy. Two new cases of this syndrome are reported. The first was in a 41-year-old man with a squamous cell carcinoma of the oesophagus, the second in a 73-year-old man who presented with a transitional cell bladder carcinoma, an association not previously reported.
