Kobayashi E, Ohsugi T, Noguchi H, Teramura M
Laboratory of Medical Engineering, Osaka Prefectural Habikino Hospital, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1993 Sep;31(9):1096-102.
We report a new method of measuring the sequential ventilation associated with the primary mechanism for ventilation inhomogeneity. Four types of sequential curves were examined using simultaneous washouts of multiple tracer boluses inhaled from residual volume (RV) and at volumes above RV. The factors that affected the classification of curves were analyzed by the theory of quantification from the statistical data of blood gases, lung function tests, X-ray and clinical diagnosis. This method was applied to evaluate the ventilation distribution in 100 patients with pulmonary disease. It provided clinical information on certain types of disease which cannot be detected by traditional lung function tests. Sequential bolus method may permit determination of whether the disease has predominantly intra or inter-regional inhomogeneity.
我们报告了一种测量与通气不均匀性主要机制相关的序贯通气的新方法。使用从残气量（RV）和高于RV的容积同时吸入的多个示踪剂团注的同时洗脱，检查了四种类型的序贯曲线。通过从血气、肺功能测试、X射线和临床诊断的统计数据进行量化理论分析影响曲线分类的因素。该方法应用于评估100例肺部疾病患者的通气分布。它提供了关于某些传统肺功能测试无法检测到的疾病类型的临床信息。序贯团注法可能有助于确定疾病主要是区域内还是区域间不均匀性。
