哺乳动物卵巢中卵母细胞与伴随卵泡细胞之间的缝隙连接。
Gap junctions between the oocyte and companion follicle cells in the mammalian ovary.
作者信息
Anderson E, Albertini D F
出版信息
J Cell Biol. 1976 Nov;71(2):680-6. doi: 10.1083/jcb.71.2.680.
Abstract
Tracer and freeze-fracture electron microscopy of the ovaries of neonatal rat and adult mouse, rat, rabbit, and primate have revealed the presence of gap junctions between follicle cells and oocytes. The junctional connections are found at the ends of follicle cell projections which traverse the zona pellucida and terminate upon microvilli and evenly contoured nonmicrovillar regions of the oolemma. Gap junctions are often seen associated with a macula adherens type of junction. The gap junctions occasionally consist of minute ovoid plaques, but nore frequently appear as rectilinear single- or multiple-row aggregates of particles on the P-face or pits on the E-face. The functional significance of follicle cell-oocyte gap junctions is discussed with respect to the regulation of meiosis and luteinization.
摘要
对新生大鼠以及成年小鼠、大鼠、兔子和灵长类动物卵巢进行示踪和冷冻断裂电子显微镜检查，发现卵泡细胞与卵母细胞之间存在间隙连接。连接连接位于卵泡细胞突起的末端，这些突起穿过透明带并终止于卵细胞膜的微绒毛和轮廓均匀的非微绒毛区域。间隙连接常与黏着斑型连接相关。间隙连接偶尔由微小的卵形斑块组成，但更常见的是在P面呈直线状单排或多排颗粒聚集体，在E面呈凹坑。本文就减数分裂和黄体化的调节对卵泡细胞 - 卵母细胞间隙连接的功能意义进行了讨论。
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