Mandell G A, Alexander M A, Harcke H T
Department of Medical Imaging, Alfred I duPont Institute, Wilmington, DE 19899.
Semin Nucl Med. 1993 Oct;23(4):334-46. doi: 10.1016/s0001-2998(05)80112-6.
Nuclear imaging in the definition of the components of the congenitally enlarged extremity is important in the design of a successful therapeutic regimen. In our series of 32 patients evaluated for primary lymphedema, 85% were determined to have abnormalities that were not purely lymphatic in origin. The multiscintigraphic approach defines the components of the lymphatic and vascular systems with the use of technetium-99m [99mTc] antimony sulfide colloid (99mTc Sb2S3) for lymphatic, 99mTc diethylenetriamine pentacetic acid (DTPA) for capillary-interstitial, and 99mTc-tagged red blood cells for venous systems.
核成像对于明确先天性肢体增大的组成部分很重要，这在成功治疗方案的设计中起着关键作用。在我们评估原发性淋巴水肿的32例患者系列中，85%被确定存在并非单纯起源于淋巴系统的异常。多闪烁显像方法利用99m锝[99mTc]硫化锑胶体（99mTc Sb2S3）来显示淋巴系统、99mTc二乙三胺五乙酸（DTPA）显示毛细血管-间质系统以及99mTc标记的红细胞显示静脉系统，以此来明确淋巴和血管系统的组成部分。
