Rutherford R B, Balis J V, Trow R S, Graves G M
J Trauma. 1976 Nov;16(11):886-97. doi: 10.1097/00005373-197611000-00007.
Hemodynamic, respiratory, and regional blood flow measurements were carried out in two groups of monkeys at three roughly equivalent stages of endotoxin and hemorrhagic shock. Comparisons revealed characteristic differences at the two early stages, particularly in systemic vascular resistance and the pattern of distribution of cardiac output. However, at the final stage of shock, these patterns had merged and there were no characteristic differences between the two groups. The pathologic significance of these findings, in terms of the endotoxin theory of irreversible hemorrhagic shock and the realtive contributions of vasoactive humoral substances at various stages of the two forms of shock, is discussed.
在内毒素性休克和失血性休克三个大致相当的阶段，对两组猴子进行了血流动力学、呼吸及局部血流测量。比较结果显示，在两个早期阶段存在特征性差异，尤其是在全身血管阻力和心输出量的分布模式方面。然而，在休克的最后阶段，这些模式已经合并，两组之间没有特征性差异。本文讨论了这些发现在内毒素性不可逆失血性休克理论以及两种休克不同阶段血管活性体液物质的相对作用方面的病理意义。
