Mark D B, Lam L C, Lee K L, Jones R H, Pryor D B, Stack R S, Williams R B, Clapp-Channing N E, Califf R M, Hlatky M A
Duke University Medical Center, Durham, North Carolina.
Ann Intern Med. 1994 Jan 15;120(2):111-7. doi: 10.7326/0003-4819-120-2-199401150-00003.
To compare return-to-work rates after coronary angioplasty, coronary bypass surgery, and medical therapy in patients with coronary disease.
Prospective cohort study.
Tertiary care referral center.
Between March 1986 and June 1990, we enrolled 1252 patients who were younger than 65 years, who had not had previous coronary revascularization, and who were employed. All patients were followed for 1 year.
One-year employment status.
After 1 year, 84% of patients who had coronary angioplasty were still working compared with 79% of patients who had bypass surgery and with 76% of patients who received medicine. After adjusting for the more favorable baseline characteristics of patients who had angioplasty (less severe coronary artery disease, better left ventricular function, and less functional impairment), however, no significant differences were noted in 1-year employment rates among the three groups. These adjusted 1-year return-to-work rates were 84% for angioplasty, 80% for surgery, and 79% for medicine (P > 0.05). In a random subset of 72 patients, 23 patients who had angioplasty returned to work after a median of 18 days (mean, 27 days) compared with 54 days (mean, 67 days) for 24 patients having bypass surgery and with 14 days (mean, 45 days) for 25 patients receiving medicine (P = 0.002).
Patients who had coronary angioplasty were able to return to work earlier than those who had bypass surgery, but by 1 year no significant difference was noted in employment rates. Neither revascularization strategy improved employment rates when compared with initial treatment using medical therapy.
比较冠心病患者接受冠状动脉血管成形术、冠状动脉搭桥手术和药物治疗后的重返工作率。
前瞻性队列研究。
三级医疗转诊中心。
在1986年3月至1990年6月期间,我们纳入了1252名年龄小于65岁、既往未接受过冠状动脉血运重建且有工作的患者。所有患者均随访1年。
1年就业状况。
1年后,接受冠状动脉血管成形术的患者中有84%仍在工作,接受搭桥手术的患者为79%,接受药物治疗的患者为76%。然而,在对接受血管成形术患者更有利的基线特征(冠状动脉疾病较轻、左心室功能较好和功能损害较小)进行调整后,三组患者的1年就业率没有显著差异。这些调整后的1年重返工作率分别为:血管成形术84%,手术80%,药物治疗79%(P>0.05)。在72名患者的随机子集中,23名接受血管成形术的患者在中位数为18天(平均27天)后重返工作,接受搭桥手术的24名患者为54天(平均67天),接受药物治疗的25名患者为14天(平均45天)(P = 0.002)。
接受冠状动脉血管成形术的患者比接受搭桥手术的患者能够更早重返工作,但到1年时,就业率没有显著差异。与初始药物治疗相比,两种血运重建策略均未提高就业率。