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钙与维生素D2口服在过敏性支气管哮喘中的应用(作者译)

[Oral application of calcium and vitamin D2 in allergic bronchial asthma (author's transl)].

作者信息

Utz G, Hauck A M

出版信息

MMW Munch Med Wochenschr. 1976 Oct 22;118(43):1395-8.

PMID:825744
Abstract

In 12 patients with allergic bronchial asthma and airway obstruction the effect of calcium in combination with vitamin D 2 (calciferol), given orally, was tested in a cross-over double blind study. Within 60 minutes after application, a statistically significant reduction of airway resistance (Rt) and intrathoracic gas volume (IGV), as well as an increase of forced exspiratory one second volume (FEV1) and forced inspiratory one second volume (FIV1) was observed, in comparison with placebo. It is concluded that calcium, given orally in combination with calciferol, causes a decrease of airway obstruction in patients with allergic bronchial asthma.

摘要

在一项交叉双盲研究中,对12例过敏性支气管哮喘和气道阻塞患者口服钙与维生素D2(骨化醇)联合使用的效果进行了测试。与安慰剂相比,给药后60分钟内,气道阻力(Rt)和胸腔内气体容积(IGV)有统计学意义的降低,同时用力呼气1秒量(FEV1)和用力吸气1秒量(FIV1)增加。得出的结论是,口服钙与骨化醇联合使用可减轻过敏性支气管哮喘患者的气道阻塞。

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