White P G, Adams H, Smith P M
Department of Radiology, Llandough Hospital NHS Trust, Penarth, South Glamorgan.
Clin Radiol. 1993 Nov;48(5):321-5. doi: 10.1016/s0009-9260(05)81240-1.
The computed tomographic (CT) appearances are described in five vinyl chloride workers with hepatic angiosarcoma subsequently confirmed at post-mortem. The tumour was multifocal in four patients. Non-enhanced scans were available in four cases showing hypodense masses relative to background liver. Dynamic scanning during intravenous contrast injection was performed in all five patients showing peripheral or central foci of enhancement within the tumour. On delayed post-contrast scans performed in three patients the angiosarcoma became wholly or partly isodense compared to normal liver. The CT appearances of angiosarcoma of the liver are non-specific but are consistent with a vascular tumour, and the differential diagnosis is discussed. Due to the vascularity of angiosarcoma, liver biopsy may be hazardous and can be avoided when there is a history of exposure to vinyl chloride monomer and the CT findings are consistent with the diagnosis.
对五名氯乙烯工人的肝脏血管肉瘤进行了计算机断层扫描(CT)检查,这些病例随后经尸检得以确诊。四名患者的肿瘤为多灶性。四例患者有平扫CT图像,显示相对于肝脏实质呈低密度肿块。所有五名患者均进行了静脉注射造影剂后的动态扫描,显示肿瘤内部有周边或中央强化灶。三名患者进行了延迟增强扫描,结果显示与正常肝脏相比,血管肉瘤全部或部分呈等密度。肝脏血管肉瘤的CT表现无特异性,但符合血管性肿瘤的特征,并对鉴别诊断进行了讨论。鉴于血管肉瘤的血管丰富性,肝活检可能具有危险性,当有接触氯乙烯单体的病史且CT表现符合诊断时,可避免进行肝活检。