单克隆抗体在肿瘤治疗中的生物学特性
Biology of monoclonal antibodies in tumor therapy.
作者信息
Janson C H
机构信息
Clinical Research Infection and Immunology, Astra Arcus AB, Södertälje, Sweden.
出版信息
Med Oncol Tumor Pharmacother. 1993;10(1-2):21-3. doi: 10.1007/BF02987764.
PMID:8258991
Abstract
This paper gives an overview of the biology of monoclonal antibodies in tumor therapy. The complexity of the monoclonal antibody concept is discussed with functional aspects on tumor antigen, antigen binding, Ig isotypes and effector mechanisms involved.
摘要
本文概述了单克隆抗体在肿瘤治疗中的生物学特性。文中讨论了单克隆抗体概念的复杂性，涉及肿瘤抗原、抗原结合、免疫球蛋白亚型及相关效应机制等功能方面。
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