Cytotoxic activity of [Pt(pyr)(N-Etlm)Cl4].
作者信息
Massacesi M, Matovic Z, Ponticelli G
机构信息
Dipartimento di Chimica e Tecnologie Inorganiche e Metallorganiche Università di Cagliari, Italy.
出版信息
Farmaco. 1993 Sep;48(9):1327-30.
PMID:8259989
Abstract
The [Pt(pyr)(N-Etlm)Cl4] complex, where pyr = pyrimidine and N-Etlm = N-ethylimidazole, previously prepared and characterized, showed an interesting cytotoxicity in vitro on the human ovarian carcinoma (A2780) and on his subline resistant to cis-platinum (A2780/CDDP), in comparison with cis-platinum and carboplatinum.
摘要
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