Rutishauser U
Department of Genetics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Curr Opin Neurobiol. 1993 Oct;3(5):709-15. doi: 10.1016/0959-4388(93)90142-l.
The structural and functional characterization of neural cell-cell adhesion molecules continues to progress at a rapid rate, exposing the complex nature of these large multidomain receptors and their intricate relationship with the cell. Over the past year, significant progress has been made in the description of multiple binding activities, signaling potentials, and cytoplasmic associations of cell-cell adhesion molecules. In addition, new modes for developmental regulation of adhesion molecule function have been identified.
神经细胞间粘附分子的结构和功能特性研究仍在快速发展,揭示了这些大型多结构域受体的复杂本质及其与细胞的复杂关系。在过去一年里,细胞间粘附分子的多种结合活性、信号转导潜力和胞质关联的描述取得了重大进展。此外,还发现了粘附分子功能发育调控的新模式。