Lander A D
Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge 02139.
Curr Opin Neurobiol. 1993 Oct;3(5):716-23. doi: 10.1016/0959-4388(93)90143-m.
Proteoglycans are ubiquitous cell-surface and secreted glycoproteins that are involved in diverse cellular behaviors. The identities of several nervous system proteoglycans, including many of the major species in the mammalian brain, have recently come to light. In addition, recent studies have given new insights into the roles of proteoglycans in nervous system development and function.
蛋白聚糖是普遍存在于细胞表面和分泌的糖蛋白,参与多种细胞行为。包括哺乳动物大脑中许多主要种类在内的几种神经系统蛋白聚糖的身份最近已被揭示。此外,最近的研究对蛋白聚糖在神经系统发育和功能中的作用有了新的认识。