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睫状神经营养因子作为一种损伤因子。

Ciliary neurotrophic factor as an injury factor.

作者信息

Adler R

机构信息

Retinal Degenerations Research Center, Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287.

出版信息

Curr Opin Neurobiol. 1993 Oct;3(5):785-9. doi: 10.1016/0959-4388(93)90154-q.

DOI:10.1016/0959-4388(93)90154-q
PMID:8260830
Abstract

This article reviews recent evidence suggesting that endogenous ciliary neurotrophic factor may be involved in neural responses to injury, and discusses the possibility that ciliary neurotrophic factor could have therapeutic applications in a clinical setting. The functional relevance of ciliary neurotrophic factor in non-injury situations is also evaluated, with emphasis on its possible roles in embryonic development.

摘要

本文综述了近期的证据，这些证据表明内源性睫状神经营养因子可能参与了对损伤的神经反应，并讨论了睫状神经营养因子在临床环境中具有治疗应用的可能性。还评估了睫状神经营养因子在非损伤情况下的功能相关性，重点关注其在胚胎发育中的可能作用。

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