Rapuano C J, Laibson P R
Cornea Service, Wills Eye Hospital, Philadephia, PA 19107.
CLAO J. 1993 Oct;19(4):235-40.
The argon-fluoride 193 nm excimer laser is currently under investigation in the United States for both refractive and therapeutic indications. We report the preliminary results of phototherapeutic keratectomy in 15 patients. Patients were divided as follows: group 1 (11 patients with anterior corneal pathology) and group 2 (four patients with refractive error after ocular surgery). Mean follow-up was 4.7 and 4.0 months in the two groups, respectively. Although results in group 1 are difficult to quantify because of varied indications, visual acuity improved in six of 11 patients (55%) and remained the same in five patients (45%). In group 2 uncorrected visual acuity improved in two patients (50%) and remained the same in two patients. Best corrected vision was the same or better in three patients but decreased four lines in one patient at 1-month follow-up, possibly related to retinal pathology. Overall, the results of excimer laser phototherapeutic keratectomy are quite promising, especially in light of alternative treatments that are more invasive.
目前，美国正在对氟化氩193纳米准分子激光用于屈光和治疗适应症进行研究。我们报告了15例患者接受光治疗性角膜切削术的初步结果。患者分为以下两组：第1组（11例有角膜前部病变的患者）和第2组（4例眼部手术后有屈光不正的患者）。两组的平均随访时间分别为4.7个月和4.0个月。尽管由于适应症不同，第1组的结果难以量化，但11例患者中有6例（55%）视力提高，5例（45%）视力保持不变。在第2组中，2例患者（50%）未矫正视力提高，2例患者视力保持不变。3例患者的最佳矫正视力相同或更好，但1例患者在1个月随访时视力下降了4行，这可能与视网膜病变有关。总体而言，准分子激光光治疗性角膜切削术的结果很有前景，尤其是考虑到其他更具侵入性的治疗方法。
