Rapuano C J, Laibson P R
Cornea Service, Wills Eye Hospital, Philadelphia, PA 19107.
CLAO J. 1994 Oct;20(4):253-7. doi: 10.1097/00140068-199410000-00012.
The argon-fluoride 193 nm excimer laser is currently under investigation in the United States for both refractive and therapeutic indications. We report the results of phototherapeutic keratectomy (PTK) on 20 eyes of 19 patients. All patients had corneal pathology in the anterior one-third of the cornea. Mean follow-up was 7.8 months. While results are difficult to quantify because of varied indications, visual acuity improved in nine of 20 eyes (45%), remained unchanged in 10 eyes (50%), and worsened in one eye (5%). We judged 15 eyes (75%) to be functionally improved and one eye (5%) to be functionally worse. Our results demonstrate the effectiveness of excimer laser PTK for a wide variety of anterior corneal conditions. With continued improvement in patient selection and refinements in hardware, software, and surgical technique, PTK holds promise as an attractive alternative to more invasive and aggressive surgery.
目前，美国正在对氟化氩193纳米准分子激光进行屈光和治疗方面的研究。我们报告了对19例患者的20只眼睛进行光治疗性角膜切削术（PTK）的结果。所有患者角膜前1/3均有病变。平均随访时间为7.8个月。由于适应证多样，结果难以量化，20只眼中9只（45%）视力提高，10只眼（50%）视力不变，1只眼（5%）视力恶化。我们判定15只眼（75%）功能改善，1只眼（5%）功能变差。我们的结果表明，准分子激光PTK对多种角膜前部疾病有效。随着患者选择的不断改进以及硬件、软件和手术技术的完善，PTK有望成为侵入性更强、更激进手术的有吸引力的替代方案。
