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穿透性巩膜角膜成形术治疗巨大复发性侵袭性鳞状细胞癌。

Penetrating sclerokeratoplasty in massive recurrent invasive squamous cell carcinoma.

机构信息

Ophthalmic Plastic & Reconstructive Surgery, Orbit, and Ocular Oncology Service, LV Prasad Eye Institute, Bhubaneswar, India.

出版信息

Ophthalmic Plast Reconstr Surg. 2011 Mar-Apr;27(2):e39-40. doi: 10.1097/IOP.0b013e3181eea1d4.

Abstract

A 35-year-old man presented with a recurrent temporal conjunctival mass (25 × 12 mm) involving about 6 clock hours of the limbus in the left eye. The mass encroached onto the temporal half of the cornea and showed surface keratin, intrinsic vasculature, and large feeder vessels. There was deep stromal infiltration. There were no cells in the anterior chamber. Ultrasound biomicroscopy confirmed infiltration of deep corneal stroma without intraocular extension. Surgery involved excision of the conjunctival component with a 4-mm margin, lamellar sclerectomy, and a penetrating sclerokeratoplasty with 3 mm of healthy corneal margin. Cryotherapy (double freeze-thaw) was done to the conjunctival margins. Histopathology showed it to be invasive squamous cell carcinoma. A thin layer of deep corneal stroma and all conjunctival margins were uninvolved. Twelve months after treatment, there was no recurrence, and the left eye recorded a visual acuity allowing finger counting at a 1-meter distance.

摘要

一位 35 岁男性,左眼出现反复发作的颞侧结膜肿块(25×12mm),累及约 6 时钟小时的角膜缘。肿块侵犯到角膜颞侧的一半,并显示表面角化、固有血管和大的供养血管。深层基质浸润。前房内没有细胞。超声生物显微镜检查证实深层角膜基质浸润,无眼内延伸。手术包括切除结膜成分,边缘 4mm,板层巩膜切除术,穿透性巩膜角膜移植术,保留 3mm 健康角膜缘。对结膜边缘进行冷冻疗法(双重冻融)。组织病理学显示为侵袭性鳞状细胞癌。深层角膜基质的薄层和所有结膜边缘均未受累。治疗 12 个月后,无复发,左眼视力记录为在 1 米距离可指数计数。

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