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通过超声检查和磁共振成像对胎儿脑部异常进行产前诊断。

Prenatal diagnosis of fetal cerebral abnormalities by ultrasonography and magnetic resonance imaging.

作者信息

D'Ercole C, Girard N, Boubli L, Potier A, Chagnon C, Raybaud C, Blanc B

机构信息

Hôpital de la Conception, Service de Gynécologie-Obstétrique, Marseille, France.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1993 Aug;50(3):177-84. doi: 10.1016/0028-2243(93)90198-l.

DOI:10.1016/0028-2243(93)90198-l
PMID:8262293
Abstract

We found magnetic resonance imaging (MRI) of the fetal brain to be effective in confirming or denying diagnosis of fetal cerebral defects when ultrasonography was inconclusive or incomplete. In this paper we describe 31 cases in which ultrasonographic evidence of fetal brain defects was verified by MRI. MRI was performed after curarization of the fetus. In 21 cases, ultrasonographic evidence was confirmed by histological study of the fetus or postnatal radiological examination. In 10 cases, ultrasonographic diagnosis was denied by MRI and healthy infants were born. In one case of cerebral toxoplasmosis, ultrasonography detected periventricular calcifications but MRI was normal. In 20 cases MRI ascertained or further documented the ultrasonographic findings. However in 4 of these 20 cases autopsy of the fetus was required to determine the exact nature of the lesion.

摘要

我们发现,当超声检查结果不明确或不完整时,胎儿脑部磁共振成像(MRI)在确诊或排除胎儿脑部缺陷方面很有效。在本文中,我们描述了31例胎儿脑部缺陷的超声证据经MRI证实的病例。MRI是在胎儿箭毒化后进行的。21例中,胎儿的组织学研究或产后放射学检查证实了超声证据。10例中,MRI否定了超声诊断,出生的婴儿健康。在1例脑弓形虫病中,超声检查发现脑室周围钙化,但MRI正常。20例中,MRI确定或进一步记录了超声检查结果。然而,在这20例中的4例中,需要对胎儿进行尸检以确定病变的确切性质。

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