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鼓室成形术中黏液纤毛清除功能对预测手术成功的预后价值。

The prognostic value of mucociliary clearance in predicting success in tympanoplasty.

作者信息

Giménez F, Marco-Algarra J

机构信息

Servicio de Otorrinolaringologia, Hospital Clinico Universitario, Universidad de Valencia, Spain.

出版信息

J Laryngol Otol. 1993 Oct;107(10):895-7. doi: 10.1017/s0022215100124727.

Abstract

Mucociliary and equipressive eustachian tube functions have been studied, using saccharin solution (five per cent sodium saccharinate) and tubal manometry respectively, in 58 ears with chronic disease undergoing tympanoplasty. The position of the perforation site determines the results as the poorest results are obtained from the posterior ones, positive cases (47 per cent) and mean transport time (37.7 minutes), compared to the greater percentage of positive cases (86 per cent) and mean transport time (22.2 minutes) for anterior perforations. When both parameters are analysed together there is a direct relationship between normal equipressive function and normal mucociliary transport time and between negative transport time and tubal blocking. Significant difference in transport times have been found for the anterior and posterior perforations being shorter for the anterior ones. When surgical outcome is correlated with mucociliary transport, the normal transport time percentage is seen to be considerably higher in the success group (50 per cent) than in the failure group (22 per cent).

摘要

分别使用糖精溶液(5%糖精钠)和咽鼓管测压法,对58例接受鼓室成形术的慢性疾病患者的耳部进行了黏液纤毛和等压咽鼓管功能研究。穿孔部位决定了结果,因为后穿孔的结果最差,阳性病例为47%,平均传输时间为37.7分钟,相比之下,前穿孔的阳性病例比例更高(86%),平均传输时间为22.2分钟。当同时分析这两个参数时,正常等压功能与正常黏液纤毛传输时间之间以及负传输时间与咽鼓管阻塞之间存在直接关系。已发现前穿孔和后穿孔的传输时间存在显著差异,前穿孔的传输时间更短。当手术结果与黏液纤毛传输相关联时,成功组的正常传输时间百分比(50%)明显高于失败组(22%)。

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