Tyson R, Welch W T, Berreen J, Wells C, Pearson C E
Department of Applied Mathematics, University of Washington, Seattle 98195.
J Theor Biol. 1993 Sep 7;164(1):15-36. doi: 10.1006/jtbi.1993.1138.
In the repair of retinal tears and detachments, the vitreous humor is often completely replaced with a temporary mixture of gases, one of which is not normally found in the bloodstream. The resulting bubble can then support the healing retina. There is diffusion of gases, however, from the bubble into the bloodstream and vice versa. This alters the intraocular pressure, with possible adverse consequences, as the intraocular pressure must be maintained within a certain range for the procedure to be successful. A simple model has been developed to predict the evolution of intraocular pressure over time, given a certain initial mixture of injected gases. This model could be useful in determining what mixture to use to support effectively and safely a healing retina.
在视网膜裂孔和脱离的修复过程中，玻璃体液常常会被一种气体的临时混合物完全替代，其中一种气体在正常情况下并不存在于血液中。由此产生的气泡随后可以支撑正在愈合的视网膜。然而，气体存在从气泡扩散到血液以及从血液扩散到气泡的情况。这会改变眼内压，可能产生不良后果，因为为了手术成功，眼内压必须维持在一定范围内。已经开发出一个简单模型，在给定一定初始注入气体混合物的情况下，预测眼内压随时间的变化。该模型有助于确定使用何种混合物来有效且安全地支撑正在愈合的视网膜。
