Abbott R, Johann-Murphy M, Shiminski-Maher T, Quartermain D, Forem S L, Gold J T, Epstein F J
Department of Neurosurgery, New York University Medical Center, New York.
Neurosurgery. 1993 Nov;33(5):851-7; discussion 857. doi: 10.1227/00006123-199311000-00010.
Selective dorsal rhizotomy has shown great promise as a treatment for the functional disabilities and deforming hypertonia of spastic cerebral palsy. At New York University Medical Center, 200 children underwent this procedure between 1986 and 1990. All groups, whether walkers, crawlers, or nonlocomotors, showed improvement in the tone and range of most muscles tested. Half of these patients experienced complications. Thirty-five of these were serious and included bronchospasm (5.5%), aspiration pneumonia (3.5%), urinary retention (7%), and sensory loss (2%). There are, however, clear indications that warn of these complications; monitoring and prophylactic treatment can minimize their effects, and the possibility of such problems is more than offset by the proven benefits of this operative procedure.
选择性背根切断术已显示出作为治疗痉挛性脑瘫功能障碍和畸形性张力亢进的巨大前景。在纽约大学医学中心,1986年至1990年间有200名儿童接受了该手术。所有组,无论是能行走的、爬行的还是不能移动的,在大多数测试肌肉的张力和活动范围方面都有改善。这些患者中有一半出现了并发症。其中35例较为严重,包括支气管痉挛(5.5%)、吸入性肺炎(3.5%)、尿潴留(7%)和感觉丧失(2%)。然而,有明确迹象可警示这些并发症;监测和预防性治疗可将其影响降至最低,而且这种手术已证实的益处远远超过了出现此类问题的可能性。