Distefano G, Tina L G, Romeo M G, Proto N, Di Pietro M, Scuderi A, Reibaldi A
Istituto di Clinica Pediatrica IIa, Università di Catania.
Pediatr Med Chir. 1993 Jul-Aug;15(4):371-6.
The authors present a retrospective epidemiological study on retinopathy of prematurity (ROP), performed on 738 newborns with a gestational age of 34 +/- 2.41 weeks and birth weight of 1971 +/- 351 g. They excluded all cases with severe respiratory distress and other pathological conditions. First stage of ROP shows no correlation with gestational age and birth weight, whereas second and third stages of ROP show an inverse correlation with the above mentioned factors, particularly birth weight. Among neonates with the same gestational age, the incidence of ROP is higher in those "small for date". Regarding the pathogenesis of ROP, the authors outline the importance of perinatal hypoxia.
作者对738例孕周为34±2.41周、出生体重为1971±351g的新生儿进行了一项关于早产儿视网膜病变（ROP）的回顾性流行病学研究。他们排除了所有患有严重呼吸窘迫和其他病理状况的病例。ROP的第一阶段与孕周和出生体重无关，而ROP的第二和第三阶段与上述因素呈负相关，尤其是出生体重。在相同孕周的新生儿中，“小于胎龄儿”的ROP发病率更高。关于ROP的发病机制，作者概述了围产期缺氧的重要性。
