Fayer R, Johnson A J, Lunde M
J Infect Dis. 1976 Dec;134(6):624-8. doi: 10.1093/infdis/134.6.624.
Six five- to eight-year-old multiparous cows were given oral inoculations of sporocysts of Sarcocystis fusiformis five to six and one-half months after field breeding. All cows became ill. Clinical signs of infection included muscle tremors, hypersalivation, reduced consumption of feed, weight loss, excessive shedding of hair, elevated temperature, reduced packed cell volumes and total red blood cell counts, and abortion. One cow aborted on day 41 after inoculation, and another aborted on day 69. A moribund cow was sacrificed, and a normal fetus was found in utero. Two cows did not produce calves; in one of these cows, a fetal skeleton was found in utero at postmortem examination. One cow produced a normal healthy calf. No evidence of congenital transmission of S. fusiformis was found in histologic specimens from the fetuses or the calf. No illness or abortion was observed in any of the 25 uninoculated control cows. This paper is the first report of bovine abortion associated with experimentally induced sarcocystosis.
六头5至8岁的经产母牛在田间配种后5至6个半月口服接种了梭形肉孢子虫的孢子囊。所有母牛均发病。感染的临床症状包括肌肉震颤、流涎过多、采食量减少、体重减轻、脱毛过多、体温升高、红细胞压积和总红细胞计数降低以及流产。一头母牛在接种后第41天流产,另一头在第69天流产。一头濒死的母牛被宰杀,子宫内发现一个正常胎儿。两头母牛未产犊;其中一头母牛在死后检查时子宫内发现一具胎儿骨骼。一头母牛产下一头正常健康的小牛。在胎儿或小牛的组织学标本中未发现梭形肉孢子虫先天性传播的证据。25头未接种的对照母牛均未出现疾病或流产。本文是关于实验性诱发肉孢子虫病导致牛流产的首次报告。