Chen Z, Silva H, Klessig D F
Waksman Institute, Rutgers, State University of New Jersey, Piscataway 08855.
Science. 1993 Dec 17;262(5141):1883-6. doi: 10.1126/science.8266079.
A complementary DNA encoding a salicylic acid (SA)-binding protein has been cloned. Its properties suggest involvement in SA-mediated induction of systemic acquired resistance (SAR) in plants. The sequence of the protein is similar to that of catalases and the protein exhibits catalase activity. Salicylic acid specifically inhibited the catalase activity in vitro and induced an increase in H2O2 concentrations in vivo. H2O2 or compounds, such as SA, that inhibit catalases or enhance the generation of H2O2, induced expression of defense-related genes associated with SAR. Thus, the action of SA in SAR is likely mediated by elevated amounts of H2O2.
一种编码水杨酸（SA）结合蛋白的互补DNA已被克隆。其特性表明它参与了植物中SA介导的系统获得性抗性（SAR）的诱导过程。该蛋白的序列与过氧化氢酶的序列相似，并且该蛋白具有过氧化氢酶活性。水杨酸在体外特异性抑制过氧化氢酶活性，并在体内诱导过氧化氢浓度升高。过氧化氢或抑制过氧化氢酶或增强过氧化氢生成的化合物（如水杨酸），诱导了与SAR相关的防御相关基因的表达。因此，SA在SAR中的作用可能是由过氧化氢量的增加介导的。
